Capitulo 1 – Download as PDF File .pdf), Text File .txt) or read online. Introducao-Bioestatística – Uploaded by. by Deborah Rumsey and if you can read in portuguese: Introdução a Bioestatística para simples mortais, by Ulysses Doria Filho) and take my. . -assassinos-e-poetas-que-sonharam-a-independencia-do-brasil-pedro-doria .

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I can show you that a patient who drinks beer at 5th day of ICU have lower mortality than a patient who does not. The median of adequate treatment for monotherapy group was ZERO! I agree that is not easy to study the same bacteria, for example, Klebsiella pneumoniae carbapenemase Gen2.

Take another look at the antibiotics doses table. In their majority, the most cited, are observational trials. And also other strange things happened.

Moving on… The eligible patients were divided in three groups: So, if Ulysse begin with polimyxin and just after 3 days add amikacin, this guy who recive amikacin is the same that our 5th day drunk guy. Keep this in mind!

Introducao-Bioestatística –

Data and results Patients in the validated polymyxin combination therapy had more severe infections and more serious disease, monotherapy group was older. This was a unicentric, retrospective study that from evaluated antibiotic combinations to guide therapy in patients with extensively drug-resistant gram negative bioestatisrica XDR GNB infections of any site.

Nothing but the whole truth. But after a multivariate analysis the authors throw bioesttatistica results saying the risk of infection related mortality is 8x greater in MT group and 6x greater in NVCT group when compared to VCT group. Combination therapy for non-believers, and believers too! The ART trial and how lung recruitment died. Now, to study Klebsiella pneumoniae carbapenemase Gen2 causing blood stream infection and compare between monotherapy vs combined therapy?


This is gonna be a revolving theme here, so keep your eyes open! Interestingly, was considered polymyxin use any of: Therefore, if you read an article showing a possible association between combined therapy and lower mortality and take this ulyssew true I can recommend you two books Statistics for Dummies, by Deborah Rumsey and if you can read in portuguese: The only group which received polymyxin at adequate dose was the VCT group.

There it is, nebulized and biestatistica are the same? If you do agree, read the literature we have available today about combination therapy. Because he had to survive our attempts to kill him as intensivists until day 5. Is biofstatistica honest to compare this group with others?

S Army — Delta associates — Memegenerator. The antibiotic dose was included in the multivariate model.

Combination therapy for non-believers, and believers too!

Both groups with combined therapy had more infections caused by Klebsiella pneumoniae and Pseudomonas aeruginosas when the monotherapy group more Acinetobacter baumannii infections. Why I hate tramadol but sometimes use it.

For me the idea of using lower doses to avoid adverse affects might increase bacterial resistance. Here we have a problem, Immortal Time Bias.

Meaning, bioestatistia you wanna treat them, do it with the right dose!


From a statistical point of view, the drinker only begin to exist at day Go hit the books then. To begin with, I can do an observational trial, either retrospective or prospective, showing that doctors who drink wine 7 days a week have more sex.

Recently I did a review of literature about introdui therapy for multi-drug resistant bacterias and soon you will see here. Therefore, beer drinkers have lower mortality than sober patients. Klysses in the validated polymyxin combination therapy had more severe infections and more serious disease, monotherapy group was older. All these information makes me wonder about the results of the multivariate analysis.

The primary outcome was infection related mortality, which was determined by the attending physician another bias here. Another thing is to realize that the study compares different sites of infection and different bacterias. Even if the patients in the VCT group were more sick, it was the only group which received adequate dose treatment. One interesting fact is that even with lot of difference among ulyswes doses no difference in nephropathy RIFLE was showed.

Patients were included if: Is the HCAP concept a lie?